HbA1c and serum levels of advanced glycation and oxidation protein products in poorly and well controlled children and adolescents with type 1 diabetes mellitus.

@article{Kostolansk2009HbA1cAS,
  title={HbA1c and serum levels of advanced glycation and oxidation protein products in poorly and well controlled children and adolescents with type 1 diabetes mellitus.},
  author={Jana Kostolansk{\'a} and Vladim{\'i}r Jaku{\vs} and L'ubom{\'i}r Bar{\'a}k},
  journal={Journal of pediatric endocrinology & metabolism : JPEM},
  year={2009},
  volume={22 5},
  pages={433-42}
}
Diabetes mellitus is associated with hyperglycemia and with accelerated non-enzymatic glycation, increased oxidative stress and free radical production. The aim of the present study was to evaluate the levels of proteins glycation and oxidation parameters, compare them between poorly and well controlled children with type 1 diabetes mellitus, and determine the impact of glycemic control on these parameters. Blood and serum were obtained from 81 patients with type 1 diabetes mellitus (DM1) (20… CONTINUE READING
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