Hb F-Urumqi G gamma I22(B4)Asp----Gly: a new fetal hemoglobin variant found in a Uygur baby.


A slowly-moving Hb F variant in a Uygur baby was detected in cord blood during a screening program carried out in Urumqi. The abnormality was located at position 22 of the gamma chain where a glycine residue replaced an aspartic acid residue. This hemoglobin also had an Ile residue in position 75 and a Gly in 136.