Corpus ID: 22038387

Hb A2-Pasteur-Tunis [delta59(E3)Lys-->Asn, AAG-->AAC]: a new delta chain variant detected by DNA sequencing in a Tunisian carrier of the codon 39 (C-->T) beta0-Thalassemia mutation.

@article{Moumni2007HbA,
  title={Hb A2-Pasteur-Tunis [delta59(E3)Lys-->Asn, AAG-->AAC]: a new delta chain variant detected by DNA sequencing in a Tunisian carrier of the codon 39 (C-->T) beta0-Thalassemia mutation.},
  author={I. Moumni and A. Zorai and Bechir Ben Daoued and I. Mosbahi and S. Omar and N. Kaabachi and K. Dellagi and S. Abb{\`e}s},
  journal={Hemoglobin},
  year={2007},
  volume={31 1},
  pages={
          23-9
        }
}
  • I. Moumni, A. Zorai, +5 authors S. Abbès
  • Published 2007
  • Medicine
  • Hemoglobin
  • We describe a new delta-globin variant, Hb A2-Pasteur-Tunis [delta59(E3)Lys-->Asn, AAG-->AAC]. This hemoglobin (Hb) displayed an electrophoretic mobility faster than normal Hb A2 and was expressed at 2.2 %. The molecular defect was characterized by DNA sequencing and confirmed by a polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP)-designed protocol. Hb A2-Pasteur-Tunis was found in a carrier of a codon 39 (C-->T) beta0-thalassemia (thal), presenting with a normal Hb… CONTINUE READING
    1 Citations
    Rare hemoglobin variants in Tunisian population