Hazard screening of photo-transformation products from pharmaceuticals: Application to selective β1-blockers atenolol and metoprolol.

@article{Toolaram2017HazardSO,
  title={Hazard screening of photo-transformation products from pharmaceuticals: Application to selective β1-blockers atenolol and metoprolol.},
  author={Anju P Toolaram and Jakob Menz and Tushar Rastogi and Christoph Leder and Klaus Kuemmerer and Mandy Schneider},
  journal={The Science of the total environment},
  year={2017},
  volume={579},
  pages={
          1769-1780
        }
}
The identification of toxic components in cocktail mixtures of pollutants, their metabolites and transformation products (TPs) generated from environmental and treatment processes remains an arduous task. This study expanded in this area by applying a combination of chemical analytics, a battery of in vitro bioassays and an in silico "testing battery" to UV photolysis mixtures of active pharmaceutical ingredients. The objectives were to understand the toxic nature of the mixtures and to… CONTINUE READING