Hawley H. Seiler Resident Award paper. The use of a miniaturized circuit and bloodless prime to avoid cerebral no-reflow after neonatal cardiopulmonary bypass.

BACKGROUND Our miniaturized bloodless prime circuit for neonatal cardiopulmonary bypass (CPB) has previously been shown to elicit significantly reduced systemic inflammation. We studied the effects of this circuit on cerebral reperfusion because the pathophysiology of "no-reflow" is believed to have an inflammatory component. METHODS Twenty neonatal… CONTINUE READING