Have we fallen off target with concerns surrounding dual RAAS blockade?

@article{Lattanzio2010HaveWF,
  title={Have we fallen off target with concerns surrounding dual RAAS blockade?},
  author={Michael R Lattanzio and Matthew R. Weir},
  journal={Kidney international},
  year={2010},
  volume={78 6},
  pages={539-45}
}
A misinterpretation of the results from ONTARGET (Ongoing Telmisartan alone and in combination with ramipril Global Endpoint Trial) has sparked both efficacy and safety concerns within the nephrology community regarding the utilization of dual RAAS blockade to achieve more desirable renal outcomes. Two important considerations are requisite prior to interpreting these results, specifically: the context of the cohort studied (non-proteinuric CKD patients at low risk of progression) and the… CONTINUE READING

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