Hashimoto's thyroiditis is associated with papillary thyroid carcinoma: role of TSH and of treatment with L-thyroxine.

@article{Fiore2011HashimotosTI,
  title={Hashimoto's thyroiditis is associated with papillary thyroid carcinoma: role of TSH and of treatment with L-thyroxine.},
  author={Emilio Fiore and Teresa Rago and Francesco Latrofa and Maria Annateresa Provenzale and Paolo Piaggi and Alessandro P Delitala and Maria Scutari and Fulvio Basolo and Giancarlo Di Coscio and Lucia Grasso and Aldo Pinchera and Paolo Vitti},
  journal={Endocrine-related cancer},
  year={2011},
  volume={18 4},
  pages={
          429-37
        }
}
The possible association between Hashimoto's thyroiditis (HT) and papillary thyroid carcinoma (PTC) is a still debated issue. We analyzed the frequency of PTC, TSH levels and thyroid autoantibodies (TAb) in 13 738 patients (9824 untreated and 3914 under l-thyroxine, l-T(4)). Patients with nodular-HT (n=1593) had high titer of TAb and/or hypothyroidism. Patients with nodular goiter (NG) were subdivided in TAb-NG (n=8812) with undetectable TAb and TAb+NG (n=3395) with positive TAb. Among… Expand

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The authors' meta-analysis confirmed that Hashimoto's thyroiditis predisposed patients to the development of papillary thyroid carcinoma (PTC). Expand
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