Harnessing the immune system to treat cancer.

  title={Harnessing the immune system to treat cancer.},
  author={Nina Bhardwaj},
  journal={The Journal of clinical investigation},
  volume={117 5},
  • Nina Bhardwaj
  • Published 2007 in The Journal of clinical investigation
A major challenge for the immune system is to recognize and eliminate cells undergoing carcinogenesis. Immune defense against tumors is complex. It can be mediated early by the innate immune system (i.e., phagocytes, NK cells, NKT cells, cytokines, and complement proteins) and later by the adaptive immune system (i.e., B cells and T cells). The eight articles in this Review series on tumor immunology discuss the mechanisms underlying immune surveillance of tumors, the regulation of… CONTINUE READING

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