Harnessing the gut to treat diabetes.

  title={Harnessing the gut to treat diabetes.},
  author={Yukihiro Fujita and Anthony Tze-Wai Cheung and Timothy J Kieffer},
  journal={Pediatric diabetes},
  volume={5 Suppl 2},
The gut contains one of the largest stem cell populations in the body, yet has been largely overlooked as a source of potentially therapeutic cells. The stem cells reside in the crypts located at the base of the protruding villi, reproduce themselves, and repopulate the gut lining as differentiated cells are sloughed off into the lumen. Some studies have demonstrated that gut stem cells can be isolated and maintained in culture, but the field is currently hampered by the lack of clear markers… CONTINUE READING