Harnessing regulatory T cells to suppress asthma: from potential to therapy.

@article{Thorburn2010HarnessingRT,
  title={Harnessing regulatory T cells to suppress asthma: from potential to therapy.},
  author={Alison N. Thorburn and Philip M Hansbro},
  journal={American journal of respiratory cell and molecular biology},
  year={2010},
  volume={43 5},
  pages={511-9}
}
Regulatory T cells (Tregs) play an essential role in maintaining the homeostatic balance of immune responses. Asthma is an inflammatory condition of the airways that is driven by dysregulated immune responses toward normally innocuous antigens. Individuals with asthma have fewer and less functional Tregs, which may lead to uncontrolled effector cell responses and promote proasthmatic responses of T helper type 2, T helper 17, natural killer T, antigen-presenting, and B cells. Tregs have the… CONTINUE READING