Harnessing a ratiometric fluorescence output from a sensor array.

  title={Harnessing a ratiometric fluorescence output from a sensor array.},
  author={Zinan Wang and Manuel A. Palacios and Grigory V. Zyryanov and Pavel Anzenbacher},
  volume={14 28},
Ratiometric fluorescence-based sensors are widely sought after because they can effectively convert even relatively small changes in optical output into a strong and easy-to-read signal. However, ratiometric sensor molecules are usually difficult to make. We present a proof-of-principle experiment that shows that efficient ratiometric sensing may be achieved by an array of two chromophores, one providing an on-to-off response and the second yielding an off-to-on response in a complementary… CONTINUE READING