Harnessing Solute Carrier Transporters for Precision Oncology

@inproceedings{Nyquist2017HarnessingSC,
  title={Harnessing Solute Carrier Transporters for Precision Oncology},
  author={Michael D. Nyquist and Bhagwat Prasad and Elahe A. Mostaghel},
  booktitle={Molecules},
  year={2017}
}
Solute Carrier (SLC) transporters are a large superfamily of transmembrane carriers involved in the regulated transport of metabolites, nutrients, ions and drugs across cellular membranes. A subset of these solute carriers play a significant role in the cellular uptake of many cancer therapeutics, ranging from chemotherapeutics such as antimetabolites, topoisomerase inhibitors, platinum-based drugs and taxanes to targeted therapies such as tyrosine kinase inhibitors. SLC transporters are co… CONTINUE READING
1
Twitter Mention

Similar Papers

Citations

Publications citing this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 132 REFERENCES