Harmonization of animal clinical pathology testing in toxicity and safety studies. The Joint Scientific Committee for International Harmonization of Clinical Pathology Testing.

@article{Weingand1996HarmonizationOA,
  title={Harmonization of animal clinical pathology testing in toxicity and safety studies. The Joint Scientific Committee for International Harmonization of Clinical Pathology Testing.},
  author={Kurt W. Weingand and Gill Brown and R P Hall and David K. Davies and Kenneth Gossett and Douglas A. Neptun and Trevor Waner and Toshiaki Matsuzawa and Paul J. M. Salemink and W Froelke and J. P. Provost and Gianni Dal Negro and Jennifer Batchelor and Masahiro Nomura and H. Gr{\"o}tsch and A. B. T. J. Boink and Janice Kimball and David Woodman and M. B. New York and E Fabianson-Johnson and M Lupart and Edon Melloni},
  journal={Fundamental and applied toxicology : official journal of the Society of Toxicology},
  year={1996},
  volume={29 2},
  pages={198-201}
}
Ten scientific organizations formed a joint international committee to provide expert recommendations for clinical pathology testing of laboratory animal species used in regulated toxicity and safety studies. For repeated-dose studies in rodent species, clinical pathology testing is necessary at study termination. Interim study testing may not be necessary in long-duration studies provided that it has been done in short-duration studies using dose levels not substantially lower than those used… CONTINUE READING

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