Harmonic intravascular ultrasound imaging with a dual-frequency catheter.


Recent studies have shown the feasibility of tissue and contrast harmonic imaging with a prototype nonlinear intravascular ultrasound (IVUS) system using a conventional single-element rotating IVUS catheter. In this study, a dual-frequency transducer element was mounted in an IVUS catheter and its second harmonic imaging performance was investigated and compared with that of a conventional IVUS catheter. Hydrophone measurements showed a transmit efficiency improvement of >6 dB for the dual-frequency catheter at 20 MHz. In vitro phantom experiments showed a signal-to noise ratio improvement of >5 dB in second harmonic mode at 40 MHz (H40) with the dual-frequency catheter, when using equal transmit voltage for both catheters. Finally, in vivo experiments were conducted and showed image improvement in H40 acquisitions with respect to the conventional IVUS catheter.

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@article{Frijlink2006HarmonicIU, title={Harmonic intravascular ultrasound imaging with a dual-frequency catheter.}, author={Martijn Frijlink and David E. Goertz and Hendrik J. Vos and Erik Tesselaar and G. Blacquiere and Andries Gisolf and Rob Krams and Antonius F.W. van der Steen}, journal={Ultrasound in medicine & biology}, year={2006}, volume={32 11}, pages={1649-54} }