Haptotactic and growth stimulatory effects of fibrin(ogen) and thrombin on cultured fibroblasts.

Abstract

We tested the ability of purified, ultraviolet C virally inactivated components of human fibrin sealant (FS) to modulate the chemotaxis, adherence, and proliferation of cultured cells. A fibrin clot formed on a near-confluent layer of human fibroblasts (HFs) recruited cells from the surrounding area. Thrombin (Thr) enhanced HF proliferation by a factor of 1… (More)

Topics

  • Presentations referencing similar topics