Haptoglobin polymorphism and chronic hepatitis C.

  title={Haptoglobin polymorphism and chronic hepatitis C.},
  author={H. K. Louagie and Johannes T. Brouwer and Joris Richard Delanghe and Marc L D De Buyzere and Geert G. Leroux-Roels},
  journal={Journal of hepatology},
  volume={25 1},
BACKGROUND/AIMS Haptoglobin (Hp) is a hemoglobin-binding acute phase protein characterized by a genetic polymorphism due to the existence of two different alleles encoding for the alpha chain of the protein. Three phenotypes have been described: Hp 1-1, Hp 2-1 and Hp 2-2. The latter two forms are known to possess immunoglobulin-like properties and play a role in the immune response. Recently, it has been shown that in subjects suffering from hepatitis C, serum Hp concentrations were lower than… CONTINUE READING
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