Haptoglobin phenotype and gestational diabetes.

  title={Haptoglobin phenotype and gestational diabetes.},
  author={Stefan Mustafa and Thomas Christian Vukovich and Thomas Prikoszovich and Christine Winzer and Barbara Taback Schneider and Harald Esterbauer and Oswald Wagner and Alexandra Kautzky-Willer},
  journal={Diabetes care},
  volume={27 9},
OBJECTIVE Haptoglobin (Hp), an Hb-binding plasma protein, exists in two major allelic variants. Hp1 has higher Hb binding and antioxidant capacity compared with Hp2. Individuals with Hp1 exhibit a lower incidence of angiopathies. Gestational diabetes mellitus (GDM) is an early manifestation of type 2 diabetes in pregnant women. It is usually confined to the time of gestation, but carries an increased risk to develop type 2 diabetes later in life. RESEARCH DESIGN AND METHODS From consecutive… CONTINUE READING
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