Haptoglobin phenotype and epithelial ovarian cancer.

  title={Haptoglobin phenotype and epithelial ovarian cancer.},
  author={Vincenzo Dario Mandato and Elena Magnani and Martino Abrate and Bruno Casali and Davide Nicoli and Enrico Farnetti and Debora Formisano and Debora Pirillo and Gino Ciarlini and Pierandrea De Iaco and Isabella Strada and Claudio Zamagni and Giovanni Battista La Sala},
  journal={Anticancer research},
  volume={32 10},
BACKGROUND Haptoglobin (H) is a glycoprotein that regulates the immune response. Serum haptoglobin levels are significantly higher in patients with advanced epithelial ovarian cancer (EOC) with poor survival. Different isoforms of haptoglobin have been found in the serum of patients with EOC. We studied the genetic susceptibility and outcome of patients with EOC correlated to H phenotypes. MATERIALS AND METHODS Analyses of the H phenotypes were performed on sera from patients stored at -70°C… CONTINUE READING


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