Haptoglobin (HP) polymorphisms and human longevity: a cross-sectional association study in a Central Italy population.

@article{Napolioni2011HaptoglobinP,
  title={Haptoglobin (HP) polymorphisms and human longevity: a cross-sectional association study in a Central Italy population.},
  author={Valerio Napolioni and Paola Giann{\`i} and Francesco Martino Carpi and Fabio Concetti and Nazzareno Lucarini},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2011},
  volume={412 7-8},
  pages={
          574-7
        }
}
BACKGROUND Haptoglobin (HP), which scavenges free, cell-toxic hemoglobin and has anti-inflammatory and immune-modulatory function in extravascular tissues, may represent an excellent candidate gene to investigate the life-span expectancy. METHODS HP 1/2 polymorphism has been determined for 1072 (569 females, 503 males) unrelated healthy individuals from Central Italy, 18-106 years old, divided into three gender-specific age classes defined according to demographic information and accounting… CONTINUE READING
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