Haptic stroke testbed for pharmacological evaluation of dynamic allodynia in mouse models

@article{Lee2018HapticST,
  title={Haptic stroke testbed for pharmacological evaluation of dynamic allodynia in mouse models},
  author={Jin Wook Lee and Brian J. Atwood and Salim Megat and Gregory Dussor and Theodore John Price and Ann Majewicz Fey},
  journal={2018 IEEE Haptics Symposium (HAPTICS)},
  year={2018},
  pages={235-240}
}
Dynamic mechanical allodynia is an aggravating neuropathological condition in which light, physical touch leads to pain. Developing pharmaceutical agents to treat this condition requires extensive animal trials using a mouse model, and a laborious process of manually stroking inflicted mouse paws, with a brush or cotton swab, while recording responses to that stimulus. In this paper, we developed an autonomous testing mechanism to create repeatable stroking sensations for mice during dynamic… 

References

SHOWING 1-10 OF 20 REFERENCES
Design and preliminary affective characterization of a novel fabric-based tactile display
TLDR
A novel wearable haptic system based on an elastic fabric which can be moved forward and backward over the user forearm thus simulating a human caress finds that phasic EDR is able to discern between pleasant and unpleasant stimuli and confirms the effectiveness of this device in conveying emotional-like haptic stimuli in a controllable and wearable fashion.
Initial study for creating linearly moving vibrotactile sensation on mobile device
TLDR
The results demonstrated that such “vibrotactile flow” can be reliably produced in a mobile device and that a performance trade-off exists depending on the method and signal duration used for rendering.
Comparison of manual and automated filaments for evaluation of neuropathic pain behavior in rats.
Assessment of pain response in capsaicin-induced dynamic mechanical allodynia using a novel and fully automated brushing device.
TLDR
A controlled, automatic brushing method can be used for quantitative investigations of allodynic reactions, and is more reliable for quantitative assessment of dynamic mechanical allodynia compared with traditional manual brushing.
Design and development of miniature wearable haptic interfaces for the fingertips
TLDR
A 2 DoF miniature haptic interface for the fingertips that allows applying shear forces in 2D, with an amplitude of movement of ±2mm and a force above 2.7N in any direction is introduced.
...
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