Hapten syntheses and antibody generation for the development of a polybrominated flame retardant ELISA.

@article{Shelver2005HaptenSA,
  title={Hapten syntheses and antibody generation for the development of a polybrominated flame retardant ELISA.},
  author={Weilin L Shelver and Young-Soo Keum and Hee-Joo Kim and Drew Rutherford and Heldur Hakk and {\AA}ke Lennart Bergman and Qing X Li},
  journal={Journal of agricultural and food chemistry},
  year={2005},
  volume={53 10},
  pages={3840-7}
}
Polybrominated diphenyl ethers (PBDEs) are a class of brominated flame retardants that are increasingly an environmental concern. Several antibodies were developed for the polybrominated diphenyl ether flame retardant BDE-47 (1), often found in the highest concentration in human milk, plasma, and adipose tissue. Four haptens with different bromine and linker substitution patterns were synthesized and utilized to generate five polyclonal antibodies from goats and two polyclonal antibodies from… CONTINUE READING

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