Haplotyping via minimum recombinant paradigm

@article{HernndezSnchez2009HaplotypingVM,
  title={Haplotyping via minimum recombinant paradigm},
  author={Jules Hern{\'a}ndez-S{\'a}nchez and Sara Knott},
  journal={BMC Proceedings},
  year={2009},
  volume={3},
  pages={S7 - S7}
}
BACKGROUND Haplotypes can increase the power of gene detection over genotypes and are essential to estimate linkage disequilibrium. METHODS Haplotyping was based on the minimum recombinant paradigm, whereby a phase is obtained only if it uniquely minimises the number of recombinants within a full sib family. Performance of this method was tested across three different data sets, consisting of genotypes and pedigree. RESULTS The percentage of phased alleles ranged from ~80% to ~95%, and the… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.
6 Citations
2 References
Similar Papers

References

Publications referenced by this paper.

Similar Papers

Loading similar papers…