Haplotypic background of a private allele at high frequency in the Americas.

  title={Haplotypic background of a private allele at high frequency in the Americas.},
  author={Kari Britt Schroeder and Mattias Jakobsson and Michael H. Crawford and Theodore G. Schurr and Simina M. Boca and Donald F. Conrad and Raul Yhossef Tito and Ludmilla P Osipova and Larissa A. Tarskaia and Sergey I. Zhadanov and Jeffrey D. Wall and Jonathan K. Pritchard and Ripan S Malhi and David G. Smith and Noah A. Rosenberg},
  journal={Molecular biology and evolution},
  volume={26 5},
Recently, the observation of a high-frequency private allele, the 9-repeat allele at microsatellite D9S1120, in all sampled Native American and Western Beringian populations has been interpreted as evidence that all modern Native Americans descend primarily from a single founding population. However, this inference assumed that all copies of the 9-repeat allele were identical by descent and that the geographic distribution of this allele had not been influenced by natural selection. To… CONTINUE READING
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