Haplotype studies support slippage as the mechanism of germline mutations in short tandem repeats

@article{Klintschar2004HaplotypeSS,
  title={Haplotype studies support slippage as the mechanism of germline mutations in short tandem repeats},
  author={M. Klintschar and E. Dauber and U. Ricci and N. Cerri and U. Immel and M. Kleiber and W. Mayr},
  journal={ELECTROPHORESIS},
  year={2004},
  volume={25}
}
Germline mutations of human short tandem repeat (STR) loci are expansions or contractions of repeat arrays which are not well understood in terms of the mechanism(s) underlying such mutations. Although polymerase slippage is generally accepted as a mechanism capable to explain most features of such mutations, it is still possible that unequal crossing over plays some role in those events, as most studies in humans could not exclude unequal crossing over (UCO). Crossing over can be studied by… Expand
Haplotype-assisted characterization of germline mutations at short tandem repeat loci
Germline mutations of STR-alleles include multi-step mutations as defined by sequencing of repeat and flanking regions.
Conservation and evolution of microsatellites in vertebrate genomes.
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