Haplotype structure and linkage disequilibrium in chemokine and chemokine receptor genes

@inproceedings{Clark2004HaplotypeSA,
  title={Haplotype structure and linkage disequilibrium in chemokine and chemokine receptor genes},
  author={Vanessa J. Clark and Michael Dean},
  booktitle={Human Genomics},
  year={2004}
}
To dissect the haplotype structure of candidate genes for disease association studies, it is important to understand the nature of genetic variation at these loci in different populations. We present a survey of haplotype structure and linkage disequilibrium of chemokine and chemokine receptor genes in 11 geographically-distinct population samples (n = 728). Chemokine proteins are involved in intercellular signalling and the immune response. These molecules are important modulators of human… CONTINUE READING
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SNPHap tool’, Innate Immunity in Heart, Lung and Blood Disease; Heart, Lung and Blood Institute, National Institutes of Health, http://www.innateimmunity.net

  • D. Clayton
  • 2003

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