Haplotype of growth hormone and angiotensin I-converting enzyme genes, serum angiotensin I-converting enzyme and ventricular growth: pathway inference in pharmacogenetics.

Abstract

OBJECTIVES An insertion/deletion (I/D) polymorphism in the angiotensin I-converting enzyme (ACE) gene is associated with variations in circulating and tissue angiotensin I-converting enzyme activity, and differences in exercise-induced left ventricular hypertrophic response. A genetic marker (CSH1.01) in the syntenic GH-CSH gene cluster correlates with… (More)

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@article{Huang2007HaplotypeOG, title={Haplotype of growth hormone and angiotensin I-converting enzyme genes, serum angiotensin I-converting enzyme and ventricular growth: pathway inference in pharmacogenetics.}, author={Shuwen Huang and Xiao-he Chen and John Payne and Dudley J. Pennell and Peter Gohlke and Matt Smith and Ian N. M. Day and Hugh E. Montgomery and Tom R. Gaunt}, journal={Pharmacogenetics and genomics}, year={2007}, volume={17 4}, pages={291-4} }