Haplotype-dependent HLA susceptibility to nasopharyngeal carcinoma in a Southern Chinese population

  title={Haplotype-dependent HLA susceptibility to nasopharyngeal carcinoma in a Southern Chinese population},
  author={Mou-ni Tang and Yu Zeng and Alice Poisson and Darlene Marti and Li B Guan and Yiqing Zheng and Hong Kui Deng and Jian Liao and Xinjian Guo and Shuzhen Sun and Gene Nelson and Guy de Th{\'e} and Cheryl A. Winkler and Stephen J. O'Brien and Mary N Carrington and Xiaojiang Gao},
  journal={Genes and Immunity},
We have conducted a comprehensive case–control study of a nasopharyngeal carcinoma (NPC) population cohort from Guangxi Province of Southern China, a region with one of the highest NPC incidences on record. A total of 1407 individuals including NPC patients, healthy controls, and their adult children were examined for the human leukocyte antigen (HLA) association, which is so far the largest NPC cohort reported for such studies. Stratified analysis performed in this study clearly demonstrated… CONTINUE READING


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