Haplotype-based, case–control study of the receptor (calcitonin) activity-modifying protein (RAMP) 1 gene in essential hypertension

Abstract

The adrenomedullin receptor is a complex molecule that comprises the calcitonin-receptor-like receptor (CRLR) and the receptor-activity-modifying protein (RAMP). RAMP1 is a vasodilation factor, and RAMP1-deficient mice (RAMP1(−/−)) exhibit inflammatory responses with a significant transient increase in serum calcitonin-gene-related peptide levels and… (More)
DOI: 10.1038/jhh.2016.96

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