Haplotype Block Structure Is Conserved across Mammals

@article{Guryev2006HaplotypeBS,
  title={Haplotype Block Structure Is Conserved across Mammals},
  author={Victor Guryev and Bart M. G. Smits and Jos{\'e} van de Belt and Mark Verheul and Norbert Hubner and Edwin Cuppen},
  journal={PLoS Genetics},
  year={2006},
  volume={2},
  pages={1197 - 1202}
}
Genetic variation in genomes is organized in haplotype blocks, and species-specific block structure is defined by differential contribution of population history effects in combination with mutation and recombination events. Haplotype maps characterize the common patterns of linkage disequilibrium in populations and have important applications in the design and interpretation of genetic experiments. Although evolutionary processes are known to drive the selection of individual polymorphisms… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

FGF-2 Gene Polymorphism in Osteoporosis among Guangxi’s Zhuang Chinese

International journal of molecular sciences • 2017
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 31 references

Genetic variation in laboratory mice

Nature Genetics • 2005
View 7 Excerpts
Highly Influenced

Unexpected complexity in the haplotypes of commonly used inbred strains of laboratory mice.

Proceedings of the National Academy of Sciences of the United States of America • 2004
View 6 Excerpts
Highly Influenced

A haplotype map of the human genome.

Nature • 2005
View 4 Excerpts
Highly Influenced

Global landscape of recent inferred Darwinian selection for Homo sapiens.

Proceedings of the National Academy of Sciences of the United States of America • 2006
View 1 Excerpt

A haplotype map of the human

D Altshuler, LD Brooks, A Chakravarti, FS Collins, MJ Daly
genome. Nature • 2005

Similar Papers

Loading similar papers…