Hanging on to your homolog: the roles of pairing, synapsis and recombination in the maintenance of homolog adhesion

@article{Walker2000HangingOT,
  title={Hanging on to your homolog: the roles of pairing, synapsis and recombination in the maintenance of homolog adhesion},
  author={Michelle Y. Walker and R. Scott Hawley},
  journal={Chromosoma},
  year={2000},
  volume={109},
  pages={3-9}
}
Homologous chromosomes initially undergo weak alignments that bring homologous sequences into register during meiosis. These alignments can be facilitated by two types of mechanisms: interstitial homology searches and telomere-telomere alignments. As prophase (and chromatin compaction) proceeds, these initial pairings or alignments need to be stabilized. In at least some organisms, such as Saccharomyces cerevisiae and S. pombe, these pairings can apparently be maintained by the creation of… CONTINUE READING

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