Handling of Dynamic Sequences in Nuclear Medicine
@article{DiPaola1982HandlingOD, title={Handling of Dynamic Sequences in Nuclear Medicine}, author={Robert Di Paola and J. P. Bazin and Florent Aubry and Andr{\'e} Aurengo and Françoise Cavailloles and J. Y. Herry and Edmond Kahn}, journal={IEEE Transactions on Nuclear Science}, year={1982}, volume={29}, pages={1310-1321} }
Nuclear Medicine is one of the first domains in which the analysis of image sequences was introduced. The development of this analysis was achieved parallel to the one of the computer systems linked to the scintillation cameras. The number of works that were performed in the research laboratories and have received an application in clinical routine is however limited. The authors indicate what could be the flow chart of the processing of dynamic sequences in scintigraphy and the kind of…
Figures from this paper
215 Citations
Dynamic single photon emission computed tomography--basic principles and cardiac applications.
- BiologyPhysics in medicine and biology
- 2010
A review of advancements toward the realization of the potential of dynamic SPECT imaging, especially in light of new developments that enable measurement of dynamic processes directly from projection measurements.
Image Sequence Processing Using Factor Analysis And Compartmental Modelling
- Computer ScienceOther Conferences
- 1989
This paper proposes an original way of introducing constraints, which is based on the a priori knowledge of the physiological data, and is applied to the study of 99mTc HMDP early kinetics in osseous tissues.
Knowledge-based factor analysis of multidimensional nuclear medicine image sequences
- Biology, MedicineMedical Imaging
- 1994
A knowledge-based approach to analyzing dynamic nuclear medicine data sets using factor analysis suggests the potential use of factor analysis in the development and evaluation of radiolabeled compounds as well as in the investigation of specific receptor systems and their role in diagnosing disease.
Reconstruction of dynamic renal tomographic data acquired by slow rotation.
- MedicineJournal of nuclear medicine : official publication, Society of Nuclear Medicine
- 2001
A new method of reconstruction of data acquired using slow camera rotations was developed using a factor model of the data in which the factors and factor coefficients were determined by modeling their relationship directly with the projection measurements.
Target apex-seeking in factor analysis of medical image sequences.
- BiologyPhysics in medicine and biology
- 1993
A new target apex-seeking method which integrates physical or physiological knowledge in this stage is described, which concerns some of the fundamental functions and reacts on the determination of all the factors.
Automated analysis of dynamic medical image series with a priori physiological knowledge
- BiologyImages of the Twenty-First Century. Proceedings of the Annual International Engineering in Medicine and Biology Society,
- 1989
The accurate quantitative analysis of dynamic image series for clinical evaluation of functional studies is investigated and the theory is applied to early kinetics of /sup 99m/Tc HMDP in osseous tissues.
Statistical distribution of factors and factor images in factor analysis of medical image sequences.
- MathematicsPhysics in medicine and biology
- 1998
It is shown how these theoretical results can be used to relax the non-negativity constraints during FAMIS oblique analysis and to improve the quantitative interpretation of the factor images by associating a confidence interval with each pixel value.
Statistical distribution of factors and factor images in factor analysis of medical image sequences
- Mathematics
- 1998
From a time or energy image sequence, factor analysis of medical image sequences (FAMIS) estimates factors, representing kinetics or spectra in a given physiological compartment, and associated…
FAMIS: a software package for functional feature extraction from biomedical multidimensional images.
- Computer ScienceComputerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
- 1992
Factor analysis: delineation of organ structures and automatic generation of in- and output functions in PET studies of prostate cancer
- Medicine2001 IEEE Nuclear Science Symposium Conference Record (Cat. No.01CH37310)
- 2001
Factor analysis was applied to dynamic PET studies to create factor images, from which ROIs were derived and input and output functions generated, which facilitated PET as a reproducible quantification method in routine oncological applications.
References
SHOWING 1-10 OF 30 REFERENCES
The use of principal components in the quantitative analysis of gamma camera dynamic studies.
- BiologyPhysics in medicine and biology
- 1980
Using a principal components analysis of the elemental curves representing the change of activity with time in each pixel, it is possible to extract the fundamental functional changes of activity which underly the observed variation of activity.
Instrumentation and data processing in cardiovascular nuclear medicine: evaluation of ventricular function.
- MedicineSeminars in nuclear medicine
- 1979
Image Processing in Nuclear Medicine
- MedicineIEEE Transactions on Nuclear Science
- 1980
A survey of various image processing techniques as applied to images in nuclear medicine is presented. These have been classified as procedures to improve detectability, to correct for distortion, to…
A Six Compartment Model for the Study of Early Kinetics of Thyroid Trap in Humans — Methodology and Results
- Medicine
- 1982
The conversational software, Clinmod, can be used for the compartmental analysis of data acquired in dynamic scintillation camera studies and the results obtained in a comparison of early iodine and technetium kinetics are described.
Fundamental Problems in Scanning.
- Medicine
- 1969
The process of radioisotopic imaging is examined in detail; discussions include capabilities of currently available scanning instruments as well as hypothetical systems; scanning limitations and possible methods of improvement are presented.
Processing of Medical Image Sequences
- Medicine
- 1981
Processing medical images has become a large and important application area of digital image processing techniques, namely X-ray images, scintigrams, ultrasonic and thermographic images, and microscopic image processing.
Three-dimensional reconstruction of isotope distributions
- Mathematics
- 1974
In the patient scanning situation with a parallel-hole collimator, it is possible to obtain a quantitative solution for the gamma emitter distribution, if attenuation is included in the calculation.…
Functional renal imaging through factor analysis.
- BiologyJournal of nuclear medicine : official publication, Society of Nuclear Medicine
- 1981
Noise in functional images is reduced by estimating parameter values from the smooth curves and accuracy is improved for the RISE parameter when curve-fitting through factor analysis is used to generate functional renal images from clinical studies or to estimate parameter values for simulated noisy renogram curves.
The Mathematical Basis of the Interpretation of Tracer Experiments in Closed Steady‐State Systems
- Physics
- 1951
The basic equation for the mixing of radioactive isotopes is dR/dt = I grad a, where dR/dt is the flux of radioactivity; a, the relative specific activity; and I, the interfusion constant. The…
Image Sequence Analysis: What Can We Learn from Applications?
- Biology
- 1981
This review is an attempt to demonstrate that progress towards more automatic evaluation of image sequences has been intimately connected with improvements of the means to construct computer-internal descriptions — loosely called ‘models’ — of the depicted scene.