Handedness in women with intrauterine exposure to diethylstilbestrol

@article{Schachter1994HandednessIW,
  title={Handedness in women with intrauterine exposure to diethylstilbestrol},
  author={Steven C. Schachter},
  journal={Neuropsychologia},
  year={1994},
  volume={32},
  pages={619-623}
}
  • S. Schachter
  • Published 1 May 1994
  • Medicine, Psychology
  • Neuropsychologia
Completed forms containing the Edinburgh handedness inventory were received from 77 women exposed to diethylstilbestrol (DES) in utero. Laterality scores (LSs; range: -100 to +100) were calculated for each respondent based on the handedness inventory and were compared with LSs from 514 female controls. The handedness distribution in the DES daughters was significantly shifted away from strong righthandedness compared with the handedness distribution in the controls (chi-square = 22.0, P < 0… 
Handedness and other laterality indices in women prenatally exposed to DES.
TLDR
It was concluded that intrauterine exposure to the synthetic estrogen DES disturbs the normal process of cerebral lateralization and laterality indices and the mechanism by which this takes place is still unknown.
Language lateralization and handedness in women prenatally exposed to diethylstilbestrol (DES)
TLDR
Women exposed prenatally to the synthetic estrogen, diethylstilbestrol (DES), and in their unexposed sisters showed an increased degree of hand preference and were more likely to be left handed for writing, but the groups did not differ significantly on a dichotic listening measure of language lateralization.
Salivary testosterone levels in left-and right-handed adults
TLDR
Results showed that LH subjects of both sexes had lower salivary T concentrations than their RH counterparts, and this is consistent with the notion that T may be involved in the development of hand preference and cerebral functional asymmetry.
Psychosexual Characteristics of Men and Women Exposed Prenatally to Diethylstilbestrol
TLDR
Overall, the findings provide little support for the hypothesis that prenatal exposure to DES influences the psychosexual characteristics of adult men and women.
Hand Preference, Sexual Preference, and Transsexualism
TLDR
Results suggest an altered pattern of cerebral hemispheric organisation in male and female transsexuals.
An examination of the influence of prenatal sex hormones on handedness: Literature review and amniotic fluid data
Competing theories have posited roles for foetal androgen exposure in the development of human handedness. However, due to practical and ethical considerations, few studies have used hormonal
Dermatoglyphics, Handedness, Sex, and Sexual Orientation
TLDR
This data indicates that heterosexual women, but not homosexual men, had highly significant increases in non–right-handedness compared with same-sex heterosexual controls, lending additional support to a biological basis of sexual orientation.
Left-handedness and risk of breast cancer
TLDR
Left-handedness may be an indicator of intrauterine exposure to oestrogens, which may increase the risk of breast cancer, and the effect was greater for post-menopausal breast cancer.
Androgenic influences on neural asymmetry: Handedness and language lateralization in individuals with congenital adrenal hyperplasia
TLDR
Results do not support the hypothesis that prenatal androgens influence language lateralization, nor do they support the Geschwind-Behan-Galaburda model that posits a key role for testosterone in the development of cognitive problems in males, secondary to changes in hemispheric development and cognitive lateralization.
Salivary testosterone is related to both handedness and degree of linguistic lateralization in normal women
TLDR
Test of the hypothesis that individual differences in testosterone (T) are associated with different patterns of linguistic lateralization and hand preference found a pattern emerged in that RH-strongly lateralized and LH-weakly lateralization women showed similar T levels.
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 33 REFERENCES
Sexual orientation after prenatal exposure to exogenous estrogen
Thirty women aged 17 to 30 years with documented prenatal exposure to the nonsteroidal synthetic estrogen diethylstilbestrol (DES) were compared to thirty women of similar demographic characteristics
Associations of handedness with hair color and learning disabilities
TLDR
Forms containing the Edinburgh handedness inventory and questions about learning disabilities, hair color, self-described handedness, age, gender, parental handedness and twinning were received from 1117 randomly selected professionals and problems in the measurement of handedness are discussed.
Measuring handedness with questionnaires
  • M. Bryden
  • Medicine, Psychology
    Neuropsychologia
  • 1977
TLDR
Factor analysis of the individual items revealed a primary handedness factor, and two factors that are idiosyncratic to the wording of the questions, which suggest shortened versions of the two tests are recommended.
Left-handedness in male-to-female transsexuals.
TLDR
Handedness provides an accessible behavioral marker that may clarify the origin of disturbed gender identity and two sources of increased sinistrality allow us to better understand prenatal and perinatal stressors.
Left-handedness in homosexual men and women: Neuroendocrine implications
TLDR
The results suggest that homosexual orientation has a neurobiological component possibly related to hemispheric functional asymmetry and the mechanisms associated with homosexual orientation and related neuropsychological characteristics are different between the sexes.
Association between left-handedness and allergy: A reappraisal
TLDR
There was no overall association between left-handedness and allergies, although it was found that left-handers may have an increased predisposition to allergic disease that manifests itself during early life.
Hormones and handedness
TLDR
It was found that girls with congenital adrenal hyperplasia (CAH) are more left-biased than their normal sisters and male CAH patients, with prenatal androgen exposure similar to that of unaffected brothers, had typical male-handedness patterns.
An epidemiological reconsideration of the Geschwind-Galaburda theory of cerebral lateralization.
TLDR
Examining the relationship of left-handedness to allergic disorders and stuttering in two French samples showed a higher frequency of stuttering but not of allergic disorders in left-handers; response bias might explain such a relationship.
The assessment and analysis of handedness: the Edinburgh inventory.
TLDR
An inventory of 20 items with a set of instructions and response- and computational-conventions is proposed and the results obtained from a young adult population numbering some 1100 individuals are reported.
Nondextrality and autoimmune disorders among relaives of language‐disabled boys
  • D. Urion
  • Psychology, Medicine
    Annals of neurology
  • 1988
TLDR
A prospective evaluation of the relatives of 100 language‐disabled boys seen in a tertiary hospital learning disabilities clinic suggests a biological heterogeneity among these families, despite a similar phenotype among all the language‐ disabled probands.
...
1
2
3
4
...