Hand-mirror cell leukemia associated with mental retardation: immunologic, chromosome, and morphological studies.

@article{Stern1979HandmirrorCL,
  title={Hand-mirror cell leukemia associated with mental retardation: immunologic, chromosome, and morphological studies.},
  author={R Stern and S T Widirstky and Doris H. Wurster-Hill and R D Allen and Kent A. Smith and G G Cornwell and Cornelius J Cornell},
  journal={Blood},
  year={1979},
  volume={54 3},
  pages={703-12}
}
Cycochemical, morphological, immunologic, and cytogenetic studies were carried out on hand-mirror cells (HMC) from a mentally retarded patient with a constitutional chromosome abnormality, 46,XX,r(21), and acute lymphoblastic leukemia. Scanning electron and differential interference contrast microscopy showed microspikes on the uropodia, but little evidence of cellular motility, despite formation and disappearance of individual uropodia in cell suspensions. The cells rosetted with sheep… CONTINUE READING
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