Hampered Lung Maturation in Methimazole-Induced Hypothyroidism in Fetal Chicken: Morphological and Molecular Correlates to Human Fetal Development.

@article{Bjrnstad2016HamperedLM,
  title={Hampered Lung Maturation in Methimazole-Induced Hypothyroidism in Fetal Chicken: Morphological and Molecular Correlates to Human Fetal Development.},
  author={Sigrid Bj\ornstad and Athina Samara and A. W. Erichsen and Ragnhild Elisabeth Paulsen and Joel Clinton Glover and Borghild Roald},
  journal={Neonatology},
  year={2016},
  volume={110 2},
  pages={83-92}
}
BACKGROUND Molecular understanding of lung development is crucial for developing therapies and diagnostic tools. Animal models with altered thyroid hormone signaling provide mechanistic insight into thyroid-dependent neonatal lung disease. Repression of Klf2 (Krüppel-like factor 2), a suggested T3 target gene, is associated with disrupted lung development… CONTINUE READING