Hamp1 but not Hamp2 regulates ferroportin in fish with two functionally distinct hepcidin types

@inproceedings{Neves2017Hamp1BN,
  title={Hamp1 but not Hamp2 regulates ferroportin in fish with two functionally distinct hepcidin types},
  author={Jo{\~a}o V Neves and Miguel Filipe Ramos and Ana Carolina Vasconcelos Moreira and Tania Pires da Silva and Maria Salom{\'e} Gomes and Pedro N. S. Rodrigues},
  booktitle={Scientific Reports},
  year={2017}
}
Hepcidin is a small cysteine rich peptide that regulates the sole known cellular iron exporter, ferroportin, effectively controlling iron metabolism. Contrary to humans, where a single hepcidin exists, many fish have two functionally distinct hepcidin types, despite having a single ferroportin gene. This raises the question of whether ferroportin is… CONTINUE READING