Hamartomatous adenoma of the nonpigmented ciliary epithelium arising in iris-ciliary body coloboma. Light and electron microscopic observations.

@article{Patrinely1983HamartomatousAO,
  title={Hamartomatous adenoma of the nonpigmented ciliary epithelium arising in iris-ciliary body coloboma. Light and electron microscopic observations.},
  author={James Randall Patrinely and Ramon L. Font and Robert J. Campbell and Dennis M. Robertson},
  journal={Ophthalmology},
  year={1983},
  volume={90 12},
  pages={
          1540-7
        }
}
A 2 1/2-year-old boy had a slowly enlarging mass at the site of a typical iris-ciliary body coloboma for 2 years. The mass was excised partially by iridocyclectomy. By light microscopy, the tumor cells were embedded in a rich mucoid stroma that contained abundant hyaluronidase-sensitive acid mucopolysaccharides. By electron microscopy the tumor showed light and dark cells with interdigitating cell membranes, desmosomes, gap junctions, multilaminar basement membrane, and numerous extracellular… 
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13 Citations

13 Citations

Citation Type

Citation Type

Congenital adenoma of the iris and ciliary body: light and electron microscopic observations.
TLDR
A 23-year-old man had a lesion in the right inferior iris which appeared to have enlarged since it was first seen when the patient was aged 5 years, and it is believed that this neoplasm represents a congenital adenoma of the ciliary body and iris.
Fetal adenoma of the pigmented ciliary epithelium associated with persistent hyperplastic primary vitreous.
TLDR
The authors report the youngest presentation of a pigment epithelium adenoma, the only well-documented case associated with persistent hyperplastic primary vitreous, and the only documentation of annulate lamellae in a ciliary body tumor.
Adenoma of the non-pigmented ciliary epithelium: a rare intraocular tumor with unusual immunohistochemical findings.
TLDR
Myofilaments are not totally unexpected in ciliary adenomas; however, such a diffuse and strong positivity for smooth muscle actin, as in the present case, has only been observed in one case before, but should be considered in the differential diagnosis of these neoplasms.
Pleomorphic adenocarcinoma of ciliary epithelium simulating an epibulbar tumor.
A 72-year-old woman had epibulbar nodules and a blind eye following trauma in childhood. Histologic examination disclosed a pleomorphic adenocarcinoma of ciliary epithelium with invasion of the…
Uncommon cause of juvenile cataract: adenoma of the nonpigmented ciliary epithelium.
TLDR
A ciliary adenoma of the nonpigmented ciliary epithelium developed in a 36-year-old woman, causing decreased visual acuity and a total cataract in the involved eye and the associated PHPV suggests a congenital origin.
Glioneuroma associated with colobomatous dysplasia of the anterior uvea and retina. A case simulating medulloepithelioma.
TLDR
The tumor was rediagnosed as glioneuroma, which in this case was part of a widespread colobomatous dysplasia of the anterior uvea and retina, and the patient is alive without metastases or local recurrence 2 years following enucleation and subtotal removal of the lesion.
Acquired neoplasms of the nonpigmented ciliary epithelium (adenoma and adenocarcinoma).
BACKGROUND/PURPOSE Acquired neoplasms of the nonpigmented ciliary body epithelium (NPCE) are rare, and most information about them has come from single case reports. This study was undertaken to…
Metastatic colloid carcinoma versus primary carcinoma of the ciliary epithelium.
Ocular metastases developed from breast carcinomas in two women 7 and 19 years after their mastectomies. They were both ciliary body metastases that had eroded through the root of the iris to present…
Ultrastructural and immunohistochemical features of coronal adenomas.
TLDR
It is confirmed that coronal adenomas develop from nonpigmented ciliary epithelium and that the extracellular material of these tumors contains components normally present in basement membranes.
Update of sporadic microphthalmos and coloboma. Non-inherited anomalies.
  • M. Warburg
  • Biology, Medicine
    Ophthalmic paediatrics and genetics
  • 1992
TLDR
This is a survey of non-inherited, sporadic microphthalmos, which may occur in the Goldenhar, CHARGE and VATER associations and may be due to teratological agents, for instance maternal ingestion of drugs, maternal infection, fever or irradiation.
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References

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TLDR
An adenoma of the non pigmented epithelium of the ciliary body was supposed to be an irisciliary body melanoma (32P-test positive) and was treated by irido-cyclectomy and showed unequivocal the benignant character of this tumor.
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TLDR
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TLDR
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agree with the premise on which the conclu­ sion is based. Preoperative antibiotics elimi­ nate the easily destroyed bacteria from the external eye and allow the resistant bacteria to multiply and…
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TLDR
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