Halothane presynaptically depresses synaptic transmission in wild-type Drosophila larvae but not in halothane-resistant (har) mutants.

@article{Nishikawa1999HalothanePD,
  title={Halothane presynaptically depresses synaptic transmission in wild-type Drosophila larvae but not in halothane-resistant (har) mutants.},
  author={Kohki Nishikawa and Yoshiaki Kidokoro},
  journal={Anesthesiology},
  year={1999},
  volume={90 6},
  pages={1691-7}
}
BACKGROUND General anesthetics produce important changes in neural function, but the relation between the many individual changes produced by anesthetics in neural components and the responsiveness of the whole organism is uncertain. An analysis of genetically altered animals that have modified responses to volatile anesthetics may help to allay this uncertainty. METHODS The authors evaluated the effect of halothane on synaptic transmission at the larval neuromuscular junction in wild-type… CONTINUE READING

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Membrane and synaptic actions of halothane on rat hippocampal pyramidal neurons and inhibitory interneurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2000
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