Halothane hepatitis.

@article{Ray1991HalothaneH,
  title={Halothane hepatitis.},
  author={David Charles Ray and GordonB. Drummond},
  journal={British journal of anaesthesia},
  year={1991},
  volume={67 1},
  pages={
          84-99
        }
}
The historical background, clinical features, morphology, epidemiology and aetiology of halothane hepatitis have been presented. Animal models of halothane hepatotoxicity have been described, although their application to humans is of doubtful significance. Two, probably distinct, forms of liver damage associated with halothane have been identified. The much more common mild form may result from reductive biotransformation of halothane, possibly influenced by genetic factors, or reduced liver… CONTINUE READING

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