Haloperidol antagonism of cue-elicited cocaine craving

@article{Berger1996HaloperidolAO,
  title={Haloperidol antagonism of cue-elicited cocaine craving},
  author={S. Paul Berger and Malcolm S. Reid and Kevin L Delucchi and Sharon Hall and Cynthia A Crawford},
  journal={The Lancet},
  year={1996},
  volume={347},
  pages={504-508}
}
  • S. Paul Berger, Malcolm S. Reid, +2 authors Cynthia A Crawford
  • Published in The Lancet 1996
  • Medicine
  • BACKGROUND Studies of cocaine-dependent subjects have shown that re-exposure to environmental cues previously associated with cocaine use produces a strong conditioned response characterised by autonomic hyperarousal and increases in subjective measures of cocaine craving. METHODS To evaluate the role of dopamine release by such cues, 20 cocaine-dependent inpatients were randomised in a single-dose, crossover, placebo-controlled design, to haloperidol (4 mg by mouth) and placebo. Plasma… CONTINUE READING

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