Haloperidol alters circadian clock gene product expression in the mouse brain.

@article{Coogan2011HaloperidolAC,
  title={Haloperidol alters circadian clock gene product expression in the mouse brain.},
  author={A N Coogan and Maria Martha Papachatzaki and Corinne Clemens and Alison Baird and Rossen M. Donev and Jozef Joosten and Venetia Zachariou and Johannes Thome},
  journal={The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry},
  year={2011},
  volume={12 8},
  pages={
          638-44
        }
}
OBJECTIVES Circadian rhythms are patterns in behavioural and physiological measures that recur on a daily basis and are driven by an endogenous circadian timekeeping system whose molecular machinery consists of a number of clock genes. The typical anti-psychotic haloperidol has previously been shown to induce significant deficiencies in circadian timing in patients. In this study we examined the impact of haloperidol treatment on molecular components of the circadian clock in the mouse brain… CONTINUE READING
BETA
1
Twitter Mention

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 10 CITATIONS

Chronotherapeutics and psychiatry: setting the clock to relieve the symptoms.

  • The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
  • 2011
VIEW 2 EXCERPTS
CITES BACKGROUND

References

Publications referenced by this paper.
SHOWING 1-10 OF 33 REFERENCES

Effect of haloperidol on mPer1 gene expression in mouse suprachiasmatic nuclei

J Viyoch, N Matsunaga, +3 authors S. Ohdo
  • J Biol Chem 280:6309
  • 2005
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Modulation of mPer1 gene expression by anxiolytic drugs in mouse cerebellum.

  • British journal of pharmacology
  • 1999
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

the expression of clock genes in the mouse hippocampus and striatum

J Viyoch, N Matsunaga, +3 authors S Ohdo
  • Neuroscience
  • 2005
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Circadian rhythms and memory formation

  • Nature Reviews Neuroscience
  • 2010
VIEW 1 EXCERPT

Impact of ageing on diurnal expression patterns of CLOCK and BMAL1 in the mouse brain

AC Wyse, Coogan AN.
  • Brain Res 1
  • 2010

Association study of 21 circadian genes with bipolar I disorder , schizoaffective disorder , and schizophrenia

L McClain, K Prasad
  • Bipolar Disord
  • 2009