Halocynthiaxanthin and Peridinin Sensitize Colon Cancer Cell Lines to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand

@article{Yoshida2007HalocynthiaxanthinAP,
  title={Halocynthiaxanthin and Peridinin Sensitize Colon Cancer Cell Lines to Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand},
  author={T. Yoshida and T. Maoka and Swadesh K. Das and K. Kanazawa and M. Horinaka and M. Wakada and Y. Satomi and H. Nishino and T. Sakai},
  journal={Molecular Cancer Research},
  year={2007},
  volume={5},
  pages={615 - 625}
}
Carotenoids are compounds contained in foods and possess anticarcinogenic activity. Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) is a promising candidate for cancer therapeutics due to its ability to induce apoptosis selectively in cancer cells. However, some tumors remain tolerant to TRAIL-induced apoptosis. Therefore, it is important to develop agents that overcome this resistance. We show, for the first time, that certain carotenoids sensitize cancer cells to TRAIL-induced… Expand
40 Citations
Combination of isoliquiritigenin and tumor necrosis factor-related apoptosis-inducing ligand induces apoptosis in colon cancer HT29 cells
Ibuprofen enhances TRAIL-induced apoptosis through DR5 upregulation.
Molecular Targets of TRAIL-Sensitizing Agents in Colorectal Cancer
Siphonaxanthin, a Green Algal Carotenoid, as a Novel Functional Compound
...
1
2
3
4
...

References

SHOWING 1-10 OF 52 REFERENCES
The combination of TRAIL and luteolin enhances apoptosis in human cervical cancer HeLa cells.
Mechanisms of resistance to TRAIL-induced apoptosis in cancer
Luteolin induces apoptosis via death receptor 5 upregulation in human malignant tumor cells
Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand
FADD Is Required for DR4- and DR5-mediated Apoptosis
Chemotherapy augments TRAIL-induced apoptosis in breast cell lines.
Safety and antitumor activity of recombinant soluble Apo2 ligand.
...
1
2
3
4
5
...