Haloacetonitriles vs. regulated haloacetic acids: are nitrogen-containing DBPs more toxic?

  title={Haloacetonitriles vs. regulated haloacetic acids: are nitrogen-containing DBPs more toxic?},
  author={Mark G Muellner and Elizabeth D Wagner and Kristin McCalla and Susan D. Richardson and Yin-tak Woo and Michael J. Plewa},
  journal={Environmental science & technology},
  volume={41 2},
Haloacetonitriles (HANs) are toxic nitrogenous drinking water disinfection byproducts (N-DBPs) and are observed with chlorine, chloramine, or chlorine dioxide disinfection. Using microplate-based Chinese hamster ovary (CHO) cell assays for chronic cytotoxicity and acute genotoxicity, we analyzed 7 HANs: iodoacetonitrile (IAN), bromoacetonitrile (BAN), dibromoacetonitrile (DBAN), bromochloroacetonitrile (BCAN), chloroacetonitrile (CAN), dichloroacetonitrile (DCAN), and trichloroacetonitrile… CONTINUE READING
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