HaloTag Technology: A Versatile Platform for Biomedical Applications

  title={HaloTag Technology: A Versatile Platform for Biomedical
  author={Christopher G. England and Haiming Luo and Weibo Cai},
  booktitle={Bioconjugate chemistry},
Exploration of protein function and interaction is critical for discovering links among genomics, proteomics, and disease state; yet, the immense complexity of proteomics found in biological systems currently limits our investigational capacity. Although affinity and autofluorescent tags are widely employed for protein analysis, these methods have been met with limited success because they lack specificity and require multiple fusion tags and genetic constructs. As an alternative approach, the… CONTINUE READING
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