Hallervorden-Spatz disease: clinical and MRI study of 11 cases diagnosed in life

  title={Hallervorden-Spatz disease: clinical and MRI study of 11 cases diagnosed in life},
  author={Lucia Angelini and Nardo Nardocci and V. Rumi and Carlo Zorzi and Liliana Strada and Mario Savoiardo},
  journal={Journal of Neurology},
SummaryThe diagnosis of Hallervorden-Spatz disease (HSD) has usually been made post mortem, although the recent description of characteristic abnormalities in the globus pallidus has suggested the possibility of an in vivo diagnosis. We present the clinical histories, neurological features and MRI findings of 11 patients, diagnosed as having HSD. Generalized dystonia with pre dominance of oromandibular involvement, behavioural changes followed by dementia and retinal degeneration were present… 

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  • J. KlepperJ. Schaper T. Voit
  • Biology, Medicine
    European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society
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