Haliclorensin, a Novel Diamino Alkaloid from the Marine Sponge Haliclonatulearensis

@article{KorenGoldshlager1998HaliclorensinAN,
  title={Haliclorensin, a Novel Diamino Alkaloid from the Marine Sponge Haliclonatulearensis},
  author={Koren-Goldshlager and Kashman and Schleyer},
  journal={Journal of natural products},
  year={1998},
  volume={61 2},
  pages={
          282-4
        }
}
Haliclorensin (1), a novel diamino alkaloid possessing an azacyclodecane ring, has been isolated from the sponge Haliclona tulearensis. Its structure was elucidated on the basis of spectroscopic data, as well as by comparison with gamma-amino azacycloalkanes. 
View on PubMed
doi.org
28 Citations
Background Citations
3

28 Citations

Citation Type

Citation Type

Halitulin, a new cytotoxic alkaloid from the marine sponge Haliclona tulearensis
1,5-Diazacyclohenicosane, a New Cytotoxic Metabolite from the Marine Sponge Mycale sp
A new cyclic diamine, 1,5-diazacyclohenicosane (1), was isolated from samples of the marine sponge Mycale sp. collected at Lamu Island (Kenya). Its structure was determined by a combination of…
A new pentacyclic sulfated hydroquinone from the marine sponge Haliclona sp.
Total synthesis of the marine alkaloid halitulin
Rapid and convergent assembly of the polycyclic framework assigned to the cytotoxic marine alkaloid halitulin
Compound 3, representing the tetra-O-methyl ether derivative of structure, 1, assigned to the cytotoxic marine alkaloid halitulin, has been assembled in a convergent manner from the readily available…
Total synthesis of the putative structure of the marine alkaloid haliclorensin
Compound 1, the structure of which has been assigned to the marine natural product haliclorensin, was prepared by an unambiguous synthetic pathway and subjected to spectroscopic analysis. The derived…
Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona
TLDR
112 nitrogenous secondary metabolites from classified and unclassified Haliclona sponges as well as from their symbiotic microorganisms display diverse bioactive properties with potential applications in new drug discovery.
Total synthesis of cytotoxic sponge alkaloids motuporamines A and B
Recent N-Atom Containing Compounds from Indo-Pacific Invertebrates
TLDR
This report presents studies on nitrogenous compounds, isolated by this group during the last few years, from Indo-Pacific sponges, one ascidian and one gorgonian, and deals with metabolites from the Madagascar sponge Fascaplysinopsis sp.
Revision of the structure of haliclorensin to (S)-7-methyl-1,5-diazacyclotetradecane and confirmation of the new structure by synthesis
...
...