Hairy is a cell context signal controlling Notch activity.

  • Yanzhen Cui
  • Published 2005 in Development, growth & differentiation


Notch signaling regulates cell fate determination and many developmental processes. Here we report that lateral inhibition, a major mechanism for Notch activity, is modulated by Hairy, a bHLH-WRPW protein. In Xenopus, Notch can have from inhibitory, permissive to enhancing roles in muscle or neural differentiation. These cell context-dependent effects… (More)

Cite this paper

@article{Cui2005HairyIA, title={Hairy is a cell context signal controlling Notch activity.}, author={Yanzhen Cui}, journal={Development, growth & differentiation}, year={2005}, volume={47 9}, pages={609-25} }