Hair roots as an mRNA source for mutation analysis of Usher syndrome-causing genes

@article{Nakanishi2010HairRA,
  title={Hair roots as an mRNA source for mutation analysis of Usher syndrome-causing genes},
  author={Hiroshi Nakanishi and Masafumi Ohtsubo and Satoshi Iwasaki and Yoshihiro Hotta and Kunihiro Mizuta and Hiroyuki Mineta and Shinsei Minoshima},
  journal={Journal of Human Genetics},
  year={2010},
  volume={55},
  pages={701-703}
}
mRNA is an important tool to study the effects of particular mutations on the mode of splicing and transcripts. However, it is often difficult to isolate mRNA because the organ or tissue in which the gene is expressed cannot be sampled. We previously identified two probable splicing mutations (c.6485+5G>A and c.8559-2A>G) during the mutation analysis of… CONTINUE READING