Hair cortisol: a parameter of chronic stress? Insights from a radiometabolism study in guinea pigs

@article{Keckeis2012HairCA,
  title={Hair cortisol: a parameter of chronic stress? Insights from a radiometabolism study in guinea pigs},
  author={Karin Keckeis and Michael Lepschy and Hanna Sch{\"o}pper and Lukas Moser and Josef Troxler and Rupert Palme},
  journal={Journal of Comparative Physiology B},
  year={2012},
  volume={182},
  pages={985-996}
}
Measurement of hair cortisol has become popular in the evaluation of chronic stress in various species. However, a sound validation is still missing. Therefore, deposition of radioactivity in hair and excretion into feces and urine after repeated injection of 3H-cortisol was studied in guinea pigs (n = 8). Each animal was given intraperitoneally 243.6 kBq 3H-cortisol/day on 3 successive days. After the first injection, all voided excreta were collected for 3 days. After the second injection… CONTINUE READING