Hair barbering in mice: Implications for neurobehavioural research

@article{Kalueff2006HairBI,
  title={Hair barbering in mice: Implications for neurobehavioural research},
  author={Allan V. Kalueff and Arevik Minasyan and Tiina Keisala and Z H Shah and Pentti Tuohimaa},
  journal={Behavioural Processes},
  year={2006},
  volume={71},
  pages={8-15}
}
Barbering (fur/whisker trimming, the Dalila effect) is a behaviour-associated hair and whisker loss frequently seen in laboratory rodents, including mice. Here we analyse barbering behaviour in 129S1, NMRI, C57BL/6 and BALB/c mouse strains and some of their F1 hybrids. Our study shows that barbering in mice, depending on their genotype, is a complex behaviour with several distinct contexts or domains. We observed social (dominant) barbering in NMRI and C57BL/6 mice, sexual over-grooming in… 
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Summary “Barbering” is an abnormal behavior in mice. Barbering mice pluck fur and/or whiskers from cage-mates and/or themselves, leaving idiosyncratic patches of hair loss. The behavior is a paradox:
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Influence of paternal genotypes on F1 behaviors: Lessons from several mouse strains
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Assessment of behavioral phenotypes of male mice of S1 and several hybrid strains implies complex interplay between parental genotypes in anxiety, activity, grooming, aggression and barbering of their F1 progeny, further confirming the utility of F1 hybrids in behavioral neurogenetics.
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In rodents, grooming is a complex and ethologically rich behavior, sensitive to stress and various genetic and pharmacological manipulations, all of which may alter its gross activity and patterning.
Analysis of Grooming Behavior and Its Utility in Studying Animal Stress, Anxiety, and Depression
In rodents, grooming is a complex and ethologically rich behavior, sensitive to stress and various genetic and pharmacological manipulations, all of which may alter its gross activity and patterning.
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Social facial touch in rats.
TLDR
Whisker trimming disrupted facial alignment and reduced the frequency of interactions, indicating that whisker use, and possibly whisker protraction, is important for rats to orient themselves with respect to one another.
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References

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TLDR
Barbering was found to occur during acts of mutual grooming and recipients were passive in accepting barbering, and even pursued conspecifics for further grooming, indicating that barbers were heavier than recipients and brain weights were not different.
Social and husbandry factors affecting the prevalence and severity of barbering (‘whisker trimming’) by laboratory mice
Abstract Barbering—the plucking of fur or whiskers from cagemates or oneself—is a common form of abnormal repetitive behavior in laboratory mice. It is often viewed as a ‘normal’ behavior of
Contrasting grooming phenotypes in three mouse strains markedly different in anxiety and activity (129S1, BALB/c and NMRI)
TLDR
Corresponding grooming phenotypes in 129S1, NMRI and BALB/c mice reflect a complex interplay between anxiety, motor and displacement activity in these strains, and ethological analysis of mouse grooming may be a useful tool in neurobehavioural research.
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TLDR
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TLDR
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TLDR
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TLDR
It is reported that mice with disruptions of Hoxb8 show, with 100% penetrance, excessive grooming leading to hair removal and lesions, and it is suggested that the excessive, pathological grooming exhibited by these mice results from CNS abnormalities.
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TLDR
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