Hafnium-doped hydroxyapatite nanoparticles with ionizing radiation for lung cancer treatment.

@article{Chen2016HafniumdopedHN,
  title={Hafnium-doped hydroxyapatite nanoparticles with ionizing radiation for lung cancer treatment.},
  author={Min-Hua Chen and Nobutaka Hanagata and Toshiyuki Ikoma and Jian-yuan Huang and Keng-Yuan Li and Chun-pin Lin and F H Lin},
  journal={Acta biomaterialia},
  year={2016},
  volume={37},
  pages={
          165-73
        }
}
UNLABELLED Recently, photodynamic therapy (PDT) is one of the new clinical options by generating cytotoxic reactive oxygen species (ROS) to kill cancer cells. However, the optical approach of PDT is limited by tissue penetration depth of visible light. In this study, we propose that a ROS-enhanced nanoparticle, hafnium-doped hydroxyapatite (Hf:HAp), which is a material to yield large quantities of ROS inside the cells when the nanoparticles are bombarded with high penetrating power of ionizing… CONTINUE READING
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